MeCHOta® CHO-K1 cell line is derived from ECACC CHO-K1, adapted to suspension culture in serum-free medium and selected by monoclonal screening, it has global authorization and proven supporting service kit(expression vector, medium), ensuring stable production capacity from laboratory to commercial scale.
Stability, compliance (traceability) and scalability (excellent metabolism) are the most important indicators for evaluating commercial engineering cell lines. MeCHOta® CHO-K1 has a clear background, complete traceability and compliance, has passed comprehensive cell testing, has reliable stability, excellent metabolic level and environmental tolerance, meets all standards of engineering cell lines, and is an excellent commercial project cell line.
Originated from ECACC CHO K1, complete purchase records, customs declaration list, temperature control records and cell COA.
Expression vectors with independent intellectual property rights and customized matching culture media.
Genetic stability across passages, consistent productivity and product quality, stable transgene integration and copy number.
Performed in CD CHO 031 basal medium using serum-free, chemically defined medium throughout the process.
Sterility, mycoplasma, endogenous viral factors, retrovirus, cell identification, etc.
Maintains low lactate levels and tolerates high ammonium and hyperosmotic conditions.
MeCHOta® CHO-K1 has uniform cell shape and size (~15μm), stable growth, short doubling time (~20h), and excellent growth characteristics. It is an ideal cell line for commercial large-scale production.
MeCHOta® CHO-K1 has a proven supporting services kit, including the expression vector system (pTOB series) with iindependent intellectual property rights, and the corresponding high-expression medium, to help customers quickly advance projects from DNA sequences to shelf products.
MeCHOta® CHO-K1 exhibits excellent stability in multiple dimensions such as copy number of exogenous genes, cDNA sequence, passaging, expression level, and expression quality, and no sequence variants are produced, meeting the requirements of commercial continuous production.
