CN EN

Antibody discovery and engineering platform

Antibody discovery and engineering modification strategy
  • Hybridoma screening
  • Phage screening
  • Humanization
  • Affinity maturation
  • Fc Silence Modification
  • Enhanced ADCC modification
  • Enhanced ADCP modification
  • Enhanced CDC modification
  • Extended Half-life modification (Fc amino acid mutation)
  • Extended half-life modification (with Anti-HSA VHH)
  • Fc heteropairing modification (Fc mutation)
  • Conjugate site modification (new Cys mutation)
  • Conjugate site modification (Sortase recognition peptide)
  • N-glycosylation site removal
  • Hot spots removal
  • Hydrophobic cluster modification
  • Charge cluster modification
  • Aggregation property modification
  • High Viscosity Property Modification
Hybridoma screening and humanization of mouse antibodies
Phage display screening and mutation library screening modification
FC Engineering